They are as simple and pure as it gets:

Vegetable Glycerin USP, Deionized Water, Organic Fruit Flavor Extract (Water, Organic Ethyl Alcohol, and Natural Flavors), Vitamin B12 (Methylcobalamin)

We NEVER use: Nicotine, Tobacco, Vitamin E Acetate, THC, Cannabinoids, Propylene Glycol, Diacetyl, or Acetyl Propionyl

Open the packaging, remove the silicone tip from the mouthpiece, and inhale from that end. Breath in and out naturally. There is no button or anything else you need to do.

Take 5-10 breaths whenever desired. There is no upper-limit on the amount of B12 you can have in any given day.

5-10 breaths is approximately 333 mcg of B12 (>8,000% Daily Value) and there are 30 such servings in each diffuser (30 x 333).

When it runs out, throw it away – you’ll know it’s out because no more vapor will come out and the LED will no longer light up.

The inhalation science of B12 dates back 60+ years. During that time, it has been shown that B12 inhalation can be orders of magnitude more efficient than oral supplementation, and completely non-toxic. Read more about the science here.

A direct quote from an academic, peer-reviewed paper on the subject tackles this question:

“To further evaluate the efficacy of pulmonary absorption of the inhaled B-12 over and above the evidence afforded by the clinical and hematological response previously described, urinary excretion studies were performed… Upon oral administration of B-12 at dosages as high as 10,000 mcgm B-12 activity in urine has been shown to be less than 0.05 millimicrograms/ml. After inhalation of only 200 mcgm of B-12 in saline, B-12 activity in the urine reached the level of 0.26 millimicrograms/ml and following inhalation of approximately 500 mcgm of B-12 in a lactose powder B-12 activity in the urine rose to 0.134 millimicrograms /ml. Direct pulmonary instillation of 100 micrograms of crystalline vitamin B-12 by means of the bronchoscope resulted in a urinary excretion (9.76 millimicrograms/ml.) pattern equivalent to the intramuscular injection of 60-80 mcgm.”

–F.J. Smith, R.W. Monto, J.W. Rebuck, “B12 Inhalation Therapy in Pernicious Anemia,” Trans Am. Clin. Climatol. Assoc. Vol. 64, p. 27 (1953).

These measurements imply that inhalation can be order(s) of magnitude more absorbent than pills.

A couple of our competitors have been rightly called-out for selling products that contain vitamins that can’t be effectively inhaled. However, vitamin B12 is an ideal candidate for inhalation and the science goes back a half century.

Those studies found that inhaling B12 was both safe and very effective. We recommend reading the primary academic literature, like this one or any of the other sources listed at the bottom of our science page.

Each diffuser is designed to last 2-3 weeks of daily use as directed. By industry standard, our atomizer has a rating of ‘700’ breaths though no one we know has ever actually achieved 700 breaths. We estimate closer to 200-300 real-world breaths.